RT Journal Article
T1 Monitoring Breathing Rate at Home Allows Early Identification of COPD Exacerbations
A1 Yañez, Aina M.
A1 Álvarez-Sala Walther, José Luis
A1 Calle Rubio, Myrian
A1 Agustí, Alvar
AB BackgroundRespiratory frequency increases during exacerbations of COPD (ECOPD). We hypothesized that this increase can be detected at home before ECOPD hospitalization.MethodsTo test this hypothesis, respiratory frequency was monitored at home daily for 3 months in 89 patients with COPD (FEV1, 42.3% ± 14.0%; reference) who were receiving domiciliary oxygen therapy (9.6 ± 4.0 h/d).ResultsDuring follow-up, 30 patients (33.7%) required hospitalization because of ECOPD. In 21 of them (70%), mean respiratory frequency increased (vs baseline) during the 5 days that preceded it (from 15.2 ± 4.3/min to 19.1 ± 5.9/min, P < .05). This was not the case in patients without ECOPD (16.1 ± 4.8/min vs 15.9 ± 4.9/min). Receiver operating characteristic analysis showed that 24 h before hospitalization, a mean increase of 4.4/min (30% from baseline) provided the best combination of sensitivity (66%) and specificity (93%) (area under the curve [AUC] = 0.79, P < .05). Two days before hospitalization, a mean increase of 2.3/min (15% change from baseline) was associated with a sensitivity of 72% and a specificity of 77% (AUC = 0.76, P < .05).ConclusionsRespiratory frequency can be monitored daily at home in patients with COPD receiving domiciliary oxygen therapy. In these patients, breathing rate increases significantly days before they require hospitalization because of ECOPD. This may offer a window of opportunity for early intervention.
PB Elsevier
SN 0012-3692
YR 2012
FD 2012-12-01
LK https://hdl.handle.net/20.500.14352/94748
UL https://hdl.handle.net/20.500.14352/94748
LA eng
NO Yañez AM, Guerrero D, Pérez de Alejo R, Garcia-Rio F, Alvarez-Sala JL, Calle-Rubio M, de Molina RM, Valle Falcones M, Ussetti P, Sauleda J, García EZ, Rodríguez-González-Moro JM, Franco Gay M, Torrent M, Agustí A. Monitoring breathing rate at home allows early identification of COPD exacerbations. Chest. 2012 Dec;142(6):1524-1529. doi: 10.1378/chest.11-2728. PMID: 22797131.
DS Docta Complutense
RD 7 abr 2025