TY  - JOUR
AU  - Azcutia Criado, Verónica
AU  - Rosetti, Florencia
AU  - Chen, Yunfeng
AU  - Sen, Mehmet
AU  - Thayer, Elizabeth
AU  - Herter, Jan M.
AU  - Luscinskas, Francis W.
AU  - Cullere, Xavier
AU  - Zhu, Cheng
AU  - Mayadas, Tanya N.
PY  - 2015
DO  - 10.1016/j.celrep.2015.02.037
UR  - https://hdl.handle.net/20.500.14352/116767
T2  - Cell Reports
AB  - Leukocyte CD18 integrins increase their affinity for ligand by transmitting allosteric signals to and from their ligand-binding αI domain. Mechanical forces induce allosteric changes that paradoxically slow dissociation by increasing the...
LA  - eng
M2  - 1655
PB  - Cell Press
KW  - Integrina Mac-1
KW  - Alostería de integrinas
KW  - Fuerzas mecánicas en la adhesión celular
KW  - Sistema inmunológico
KW  - Lupus
TI  - A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force
TY  - journal article
VL  - 10
ER  -