RT Journal Article
T1 Distinct Expression Profiles of Three Melatonin Receptors during Early Development and Metamorphosis in the Flatfish Solea senegalensis
A1 Lan-Chow-Wing, Olivier
A1 Confente, Francesca
A1 Herrera-Pérez, Patricia
A1 Isorna Alonso, Esther
A1 Chereguini, Olvido
A1 Rendón, Maria
A1 Falcón, Jack
A1 Muñoz-Cueto, José
AB Melatonin actions are mediated through G protein-coupled transmembrane receptors. Recently, mt1, mt2, and mel1c melatonin receptors were cloned in the Senegalese sole. Here, their day-night and developmental expressions were analyzed by quantitative PCR. These results revealed distinct expression patterns of each receptor through development. mel1c transcripts were more abundant in unfertilized ovulated oocytes and declined during embryonic development. mt1 and mt2 expression was higher at the earliest stages (2–6 days post-fertilization), decreasing before (mt2) or during (mt1) metamorphosis. Only mt1 and mel1c expression exhibited day-night variations, with higher nocturnal mRNA levels. These results suggest different roles and transcriptional regulation of these melatonin receptors during flatfish development and metamorphosis.
PB MDPI
SN 1422-0067
YR 2014
FD 2014-11-13
LK https://hdl.handle.net/20.500.14352/34319
UL https://hdl.handle.net/20.500.14352/34319
LA eng
NO Ministerio de Economía y Competitividad (MINECO)
DS Docta Complutense
RD 9 abr 2025