RT Journal Article
T1 Skin Bioimpedance Analysis to Determine Cellular Integrity by Phase Angle in Women with Fibromyalgia: A Cross-Sectional Study
A1 Vicente Campos, Davinia
A1 Sánchez Jorge, Sandra
A1 Martí, Luis
A1 Buffet, Jorge
A1 Mendoza Laiz, Nuria
A1 Rodríguez Sanz, David
A1 Becerro De Bengoa Vallejo, Ricardo
A1 Chicarro, J. L.
A1 Calvo Lobo, César
AB Oxidative stress has been proposed as a significant part of the pathogenesis of fibromyalgia, and the phase angle in bioelectrical impedance analysis has been explored as a potential technique to screen oxidative abnormalities. This study recruited 35 women with fibromyalgia and 35 healthy women, who underwent bioelectrical impedance analysis and maximum isometric handgrip strength tests. Women with fibromyalgia showed lower bilateral handgrip strength (right hand: 16.39 ± 5.87 vs. 27.53 ± 4.09, p < 0.001; left hand: 16.31 ± 5.51 vs. 27.61 ± 4.14, p < 0.001), as well as higher body fat mass (27.14 ± 10.21 vs. 19.94 ± 7.25, p = 0.002), body fat percentage (37.80 ± 8.32 vs. 30.63 ± 7.77, p < 0.001), and visceral fat area (136.76 ± 55.31 vs. 91.65 ± 42.04, p < 0.01) compared with healthy women. There was no statistically significant difference in muscle mass between groups, but women with fibromyalgia showed lower phase angles in all body regions when compared with healthy control women (right arm: 4.42 ± 0.51 vs. 4.97 ± 0.48, p < 0.01; left arm: 4.23 ± 0.48 vs. 4.78 ± 0.50, p < 0.001; trunk: 5.62 ± 0.77 vs. 6.78 ± 0.84, p < 0.001; right leg: 5.28 ± 0.56 vs. 5.81 ± 0.60, p < 0.001; left leg: 5.07 ± 0.51 vs. 5.69 ± 0.58, p < 0.001; whole body: 4.81 ± 0.47 vs. 5.39 ± 0.49, p < 0.001). Moreover, whole-body phase-angle reduction was only predicted by the presence of fibromyalgia (R2 = 0.264; β = 0.639; F(1,68) = 24.411; p < 0.001). Our study revealed significantly lower phase angle values, lower handgrip strength, and higher fat levels in women with fibromyalgia compared to healthy controls, which are data of clinical relevance when dealing with such patients.
PB MDPI
SN 2227-9059
YR 2023
FD 2023-12-15
LK https://hdl.handle.net/20.500.14352/110744
UL https://hdl.handle.net/20.500.14352/110744
LA eng
NO Vicente-Campos, D.; Sánchez-Jorge, S.; Martí, L.; Buffet, J.; Mendoza-Laiz, N.; Rodriguez-Sanz, D.; Becerro-de-Bengoa-Vallejo, R.; Chicarro, J.L.; Calvo-Lobo, C. Skin Bioimpedance Analysis to Determine Cellular Integrity by Phase Angle in Women with Fibromyalgia: A Cross-Sectional Study. Biomedicines 2023, 11, 3321. https://doi.org/10.3390/biomedicines11123321
NO 2023 Descuento MDPI
DS Docta Complutense
RD 10 abr 2025