TY - JOUR AU - López Millán, Belén AU - Costales, Paula AU - Gutiérrez Agüera, Francisco AU - Díaz de la Guardia, Rafael AU - Roca Ho, Heleia AU - Vinyoles, Meritxell AU - Rubio Gayarre, Alba AU - Safi, Rémi AU - Castaño, Julio AU - Romecín, Paola Alejandra AU - Ramirez Orellana, Manuel AU - Anguita Mandly, Eduardo Luis AU - Jeremías, Irmela AU - Zamora, Lurdes AU - Rodríguez Manzaneque, Juan Carlos AU - Bueno, Clara AU - Morís, Francisco AU - Menéndez, Pablo PY - 2022 DO - 10.3390/cancers14061593 SN - 2072-6694 UR - https://hdl.handle.net/20.500.14352/71621 T2 - Cancers AB - Patients with AML harboring constitutively active mutations in the FLT3 receptor generally have a poor prognosis (FLT3-ITDMUT). Despite the fact that several FLT3 inhibitors have been developed, clinical responses are commonly partial or not durable,... LA - eng M2 - 1593 PB - MPDI KW - AML KW - EC-70124 multi-kinase inhibitor KW - FLT3-ITD mutation KW - FLT3 inhibitor KW - AML preclinical model TI - The Multi-Kinase Inhibitor EC-70124 Is a Promising Candidate for the Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia TY - journal article VL - 14 ER -