TY - JOUR AU - García Cuesta, Eva M AU - Rodríguez Frade, José Miguel AU - Gardeta, Sofía R AU - D'Agostino, Gianluca AU - Martínez, Pablo AU - Soler Palacios, Blanca AU - Cascio, Graciela AU - Wolf, Tobias AU - Mateos, Nicolas AU - Ayala Bueno, Rosa AU - Santiago, César A AU - Lucas, Pilar AU - Llorente, Lucia AU - Allende Martínez, Luis Miguel AU - González Granado, Luis Ignacio AU - Martín Cófreces, Noa AU - Roda Navarro, Pedro AU - Sallusto, Federica AU - Sánchez Madrid, Francisco AU - García Parajo, María F AU - Martínez Muñoz, Laura AU - Mellado, Mario PY - 2022 UR - https://hdl.handle.net/20.500.14352/120087 T2 - Proceedings of the National Academy of Sciences of the United States of America AB - Chemokine receptor nanoscale organization at the cell membrane is orchestrated by the actin cytoskeleton and influences cell responses. Using single-particle tracking analysis we show that CXCR4R334X, a truncated mutant chemokine receptor linked to... LA - eng PB - National Academy of Sciences KW - WHIM syndrome KW - cell migration KW - chemokine receptors TI - Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients. TY - journal article VL - 119 ER -