RT Journal Article
T1 Impact of Type 2 Diabetes Mellitus on the Incidence and Outcomes of COVID-19 Needing Hospital Admission According to Sex: Retrospective Cohort Study Using Hospital Discharge Data in Spain, Year 2020
A1 Miguel Yanes, José María De
A1 Jiménez García, Rodrigo
A1 Miguel Díez, Javier De
A1 Hernández Barrera, Valentín
A1 Carabantes Alarcón, David
A1 Zamorano León, José Javier
A1 Omaña Palanco, Ricardo
A1 López De Andrés, Ana Isabel
AB (1) Background: To analyze incidence and in-hospital mortality (IHM) of COVID-19 needing hospital admission in Spain (2020) in patients with T2DM. (2) Methods: We conducted a retrospective cohort study. Using the Spanish Register of Specialized Care-Basic Minimum Database we estimated age-adjusted incidence rates (IR). (3) Results: We included 203,488 patients (56.77% men), of whom 45,620 (22.41%) had T2DM. Age-adjusted IRs/1000 for men with and without T2DM was 12.90 and 5.87, respectively (IRR 2.20; 95% CI 2.18–2.22; p < 0.001), and for women with and without T2DM was 9.23 and 4.27, respectively (IRR 2.16; 95% CI 2.13–2.19; p < 0.001). Crude IHM was 23.86% in people with T2DM, and 15.94% in non-T2DM people (p < 0.001). After matching, intensive-care admission (7.37% vs. 6.15%; p < 0.001) and IHM (23.37% vs. 20.41%; p < 0.001) remained higher in women with T2DM. After matching, IHM among T2DM men was 1.5% higher than among non-T2DM men (24.27% vs. 22.72%; p < 0.001). Men with T2DM had a 34% higher IHM than women with T2DM. Prevalent T2DM increased IHM among women (1.09; 95% 1.03–1.16) and men (1.05; 95% 1.01–1.10). (4) Conclusions: Incidence rates of COVID-19 needing hospital admission were higher in men vs. women, and for people with T2DM vs. non-T2DM. Men had higher IHM beside T2DM status. Prevalent T2DM was associated with higher IHM for both sexes.
PB MPDI
SN 2077-0383
YR 2022
FD 2022-05-09
LK https://hdl.handle.net/20.500.14352/71724
UL https://hdl.handle.net/20.500.14352/71724
LA eng
NO Miguel Yanes, J. M., Jiménez García, R., Miguel Díez, J. et al. «Impact of Type 2 Diabetes Mellitus on the Incidence and Outcomes of COVID-19 Needing Hospital Admission According to Sex: Retrospective Cohort Study Using Hospital Discharge Data in Spain, Year 2020». Journal of Clinical Medicine, vol. 11, n.o 9, mayo de 2022, p. 2654. DOI.org (Crossref), https://doi.org/10.3390/jcm11092654.
NO Instituto de Salud Carlos III/Fondo Europeo de Desarrollo Regional
NO Universidad Complutense de Madrid/Comunidad de Madrid
NO UCM: Grupo de Investigación en Epidemiología de las Enfermedades Crónicas de Alta Prevalencia en España
DS Docta Complutense
RD 7 abr 2025