TY  - JOUR
AU  - Zhou, Nan
AU  - Gutiérrez Uzquiza, Álvaro
AU  - Zheng, Xiang Yu
AU  - Chang, Renxu
AU  - Vogl, Dan T.
AU  - Garfall, Alfred L.
AU  - Bernabei, Luca
AU  - Saraf, Anita
AU  - Florens, Laurence
AU  - Washburn, Michael P
AU  - Illendula, Anuradha
AU  - Bushweller, John H.
AU  - Busino, Luca
PY  - 2019
DO  - 10.1038/s41375-019-0403-2
SN  - 0887-6924
SN  - 1476-5551
UR  - https://hdl.handle.net/20.500.14352/115292
T2  - Leukemia
AB  - Ikaros family zinc finger protein 1 and 3 (IKZF1 and IKZF3) are transcription factors that promote multiple myeloma (MM) proliferation. The immunomodulatory imide drug (IMiD) lenalidomide promotes myeloma cell death via Cereblon (CRBN)- dependent...
LA  - eng
PB  - Springer-Nature
TI  - RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation
TY  - journal article
VL  - 37
ER  -