RT Journal Article
T1 Cardiac magnetic resonance determinants of functional mitral regurgitation in ischemic and non ischemic left ventricular dysfunction
A1 Fernández Golfín, Covadonga
A1 De Agustín Loeches, José Alberto
A1 Manzano, M. Carmen
A1 Bustos García De Castro, Ana María
A1 Sánchez, Tibisay
A1 Pérez De Isla, Leopoldo
A1 Fuentes Ramos, Manuel
A1 Macaya Miguel, Carlos
A1 Zamorano Gómez, José Luis
AB Functional mitral regurgitation (FMR) is frequent in left ventricular (LV) dilatation/dysfunction. Echocardiographic predictors of FMR are known. However, cardiac magnetic resonance (CMR) predictors of FMR have not been fully addressed. The aim of the study was to evaluate CMR mitral valve (MV) parameters associated with FMR in ischemic and non ischemic LV dysfunction. 80 patients with LV ejection fraction below 45% and/or left ventricular dilatation of ischemic and non ischemic etiology were included. Cine-MR images (steady state free-precession) were acquired in a short-axis and 4 chambers views where MV evaluation was performed. Delayed enhancement was performed as well. Significant FMR was established as more than mild MR according to the echocardiographic report. Mean age was 59 years, males 79%. FMR was detected in 20 patients (25%) Significant differences were noted in LV functional parameters and in most MV parameters according to the presence of significant FMR. However, differences were noted between ischemic and non ischemic groups. In the first, differences in most MV parameters remained significant while in the non ischemic, only systolic and diastolic interpapillary muscle distance (1.60 vs. 2.19 cm, P = 0.001; 2. 51 vs. 3.04, P = 0.008) were predictors of FMR. FMR is associated with a more severe LV dilatation/dysfunction in the overall population. CMR MV parameters are associated with the presence of significant FMR and are different between ischemic and non ischemic patients. CMR evaluation of these patients may help in risk stratification as well as in surgical candidate selection.
PB Nature
SN 1569-5794
YR 2011
FD 2011-09-08
LK https://hdl.handle.net/20.500.14352/133624
UL https://hdl.handle.net/20.500.14352/133624
LA eng
NO Fernández-Golfín C, De Agustin A, Manzano MC, Bustos A, Sánchez T, Pérez de Isla L, Fuentes M, Macaya C, Zamorano J. Cardiac magnetic resonance determinants of functional mitral regurgitation in ischemic and non ischemic left ventricular dysfunction. Int J Cardiovasc Imaging. 2011 Apr;27(4):539-46. doi: 10.1007/s10554-010-9696-y
DS Docta Complutense
RD 9 mar 2026