TY - JOUR AU - Arias, Clemente F. AU - Herrero García, Miguel Ángel AU - Cuesta, José A. AU - Acosta Salmerón, Francisco Javier AU - Fernández Arias, Cristina PY - 2015 DO - 10.1098/rsos.150016 SN - 2054-5703 UR - https://hdl.handle.net/20.500.14352/96049 T2 - Royal Society Open Science AB - Adaptive immune responses depend on the capacity of T cells to target specific antigens. As similar antigens can be expressed by pathogens and host cells, the question naturally arises of how can T cells discriminate friends from foes. In this work,... LA - eng PB - The Royal Society KW - T cells KW - immune self KW - immune tolerance KW - immunodominance KW - negative selection TI - The growth thresh- old conjecture: a theoretical framework for understanding T-cell tolerance TY - journal article VL - 2 ER -