TY - JOUR AU - Notario Pérez, Fernando AU - Cazorla Luna, Raúl AU - Martín Illana, Araceli AU - Ruiz Caro, Roberto AU - Peña López, Juan AU - Veiga Ochoa, María Dolores PY - 2019 DO - 10.3390/pharmaceutics11030137 SN - 1999-4923 UR - https://hdl.handle.net/20.500.14352/12756 T2 - Pharmaceutics AB - Hot-melt granulation is a technique used to obtain granules by dispersing a drug in polymers at a high temperature. Tenofovir, an antiretroviral drug with proven activity as a vaginal microbicide, was dispersed in melted Gelucire® (or a mixture of... LA - eng M2 - 137 PB - MDPI KW - Controlled release KW - Ex vivo bioadhesion KW - Gelucire® KW - Human Immunodeficiency Virus KW - Mucoadhesive vaginal compacts KW - Tenofovir TI - Tenofovir Hot-Melt Granulation using Gelucire® to Develop Sustained-Release Vaginal Systems for Weekly Protection against Sexual Transmission of HIV TY - journal article VL - 11 ER -