RT Journal Article
T1 The Profile of the Obstetric Patients with SARS-CoV-2 Infection According to Country of Origin of the Publication: A Systematic Review of the Literature
A1 Cuñarro López, Yolanda
A1 Pintado Recarte, Pilar
A1 Cueto Hernández, Ignacio
A1 Hernández Martín, Concepción
A1 Payá Martínez, María Pilar
A1 Muñóz Chápuli, María del Mar
A1 Cano Valderrama, Óscar
A1 Bravo Arribas, Coral
A1 Bujan, Julia
A1 Álvarez Mon, Melchor
A1 Ortega, Miguel A.
A1 De León Luis, Juan Antonio
AB SARS-CoV-2 is the novel member of coronavirus responsible for the worldwide pandemic COVID-19, affecting all types of people. In this context, established research identified pregnant women as a susceptible group of SARS-CoV-2 infection, although there is still limited data regarding the real impact of COVID-19 in this group. With that purpose, we conducted a systematic review describing the maternal-fetal results of pregnant women infected by SARS-CoV-2, in aim to analyze the profile of the obstetric patients according to the country of origin of the publication. A total of 38 articles were included in this systematic review with 2670 patients from 7 countries, with 20 works published from China (52.6%). We reported significative differences according to the median maternal age, with Spain as the country with the highest age (34.6 years); The percentage of tabaquism; proportion of symptomatic patients in the triage; type of radiological exam (China and France conduct CT scans on all their patients in comparison to the use of chest X-Ray in the rest of the countries studied); percentages of C-sections (83.9% in China; 35.9% Spain, p < 0.001); maternal mortality rate, proportion of patients who need treatments, the use of antivirals, antibiotics, and anticoagulants as well as measurements of the newborns. Perinatal results are favorable in the majority of countries, with very low rates of vertical transmission in the majority of works. The studies collected in this review showed moderate to high index of quality. The different works describe the affectation during the first wave of the pandemic, where the pregnant woman with SARS-CoV-2 infection is generally symptomatic during the third trimester of gestation along with other factors associated with worse prognosis of the disease, such as higher age, body mass index, and further comorbidities developed during pregnancy. In the obstetric patient, proportion of C-sections are elevated together with prematurity, increasing maternal perinatal morbimortality. Differences found between countries could be based on the proper profile of the patient in each region, the period of the pandemic directly affecting how it was managed, and the variations regarding in situ medical attention.
PB MDPI
SN 2077-0383
YR 2021
FD 2021-01-19
LK https://hdl.handle.net/20.500.14352/7351
UL https://hdl.handle.net/20.500.14352/7351
LA eng
NO Cuñarro-López Y, Pintado-Recarte P, Cueto-Hernández I, Hernández-Martín C, Payá-Martínez MP, Muñóz-Chápuli MDM, et al. The Profile of the Obstetric Patients with SARS-CoV-2 Infection According to Country of Origin of the Publication: A Systematic Review of the Literature. JCM 2021;10:360. https://doi.org/10.3390/jcm10020360.
NO The research was funded by the University of Alcalá (COVID-19 UAH 2019/00003/016/001/023) and by (FIS-PI18/00912) the Instituto de Salud Carlos III (Plan Estatal de I + D+I 2013-2016) and cofinanced by the European Development Regional Fund “A way to achieve Europe” (ERDF) and B2017/BMD-3804 MITIC-CM.
NO Unión Europea
NO Comunidad de Madrid
NO Universidad de Alcalá
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 30 sept 2024