TY - JOUR AU - Chinchilla Rodríguez, Blanca AU - Foltopoulou, Parthena AU - Fernandez Godino, Rosario PY - 2021 DO - 10.1002/path.5747 SN - 0022-3417 UR - https://hdl.handle.net/20.500.14352/116680 T2 - Journal of Pathology AB - Despite numerous unsuccessful clinical trials for anti-complement drugs to treat age-related macular degeneration(AMD), the complement system has not been fully explored as a target to stop drusen growth in patients with dry AMD. We propose that the... LA - eng M2 - 120 PB - Wiley Online Library KW - Tick-over KW - Complement KW - Retinal pigment epithelium KW - Basal deposits KW - Age-related macular degeneration TI - Tick-over-mediated complement activation is sufficient to cause basal deposit formation in cell-based models of macular degeneration TY - journal article ER -