RT Journal Article
T1 Neural Mechanisms in Eating Behaviors: A Pilot fMRI Study of Emotional Processing
A1 Molina Ruiz, Rosa M.
A1 García Saiz, T.
A1 Looi, Jeffrey C.L.
A1 Via Virgili, E.
A1 Rincón Zamorano, M.
A1 de Anta Tejado, Laura
A1 López, Helena Trebbau
A1 Carrasco Perera, José Luis
A1 Díaz Marsa, Marina Francisca
AB ObjectiveEmotional processing dysfunction evident in eating disorders (ED) such as anorexia nervosa (AN) and bulimia nervosa (BN), is considered relevant to the development and maintenance of these disorders. The purpose of the current functional magnetic resonance imaging (fMRI) study was to pilot a comparison of the activity of the fronto-limbic and fronto-striatal brain areas during an emotion processing task in persons with ED.Methods24 women patients with ED were scanned, while showing emotionally stimulating (pleasant, unpleasant) and neutral images from the International Affective Picture System (IAPS).ResultsDuring the pleasant condition, significant differences in Dorsolateral Prefrontal Cortex (DLPFC) activations were found with AN participants presenting greater activation compared to BN and ED comorbid groups (EDc) and healthy controls also showing greater activation of this brain area compared to BN and EDc. Left putamen was less activated in EDc compared to both controls (C) and AN. During the unpleasant condition, AN participants showed hyperactivation of the Orbito-Frontal Cortex (OFC) when compared to EDc.ConclusionThis study highlights the potential functional relevance of brain areas that have been associated with self-control. These findings should help advance understanding the neural substrate of ED, though they should be considered as preliminary and be cautiously interpreted.
PB Korean Neuropsychiatric Association
SN 1738-3684
SN 1976-3026
YR 2020
FD 2020-03-25
LK https://hdl.handle.net/20.500.14352/131258
UL https://hdl.handle.net/20.500.14352/131258
LA eng
NO Molina-Ruiz RM, García-Saiz T, Looi JCL, Via Virgili E, Rincón Zamorano M, De Anta Tejado L, et al. Neural Mechanisms in Eating Behaviors: A Pilot fMRI Study of Emotional Processing. Psychiatry Investig 2020;17:225–36. https://doi.org/10.30773/pi.2019.0038.
DS Docta Complutense
RD 25 abr 2026