RT Journal Article
T1 Modulation of crystallinity through radiofrequency electromagnetic fields in PLLA/magnetic nanoparticles composites: A proof of concept
A1 Multigner, Marta
A1 Morales, Irene
A1 Giacomone, Fernando
A1 Presa Muñoz De Toro, Patricia Marcela De La
A1 Benavente, Rosario
A1 Torres, Belén
A1 Mantovani, Diego
A1 Rams, Joaquín
AB To modulate the properties of degradable implants from outside of the human body represents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nanoparticles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f center dot H < 5 center dot x 10_(9) Am_(-1) center dot s_(-1). Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were analyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.
PB MDPI
SN 1996-1944
YR 2021
FD 2021-08
LK https://hdl.handle.net/20.500.14352/5066
UL https://hdl.handle.net/20.500.14352/5066
LA eng
NO © 2021 by the authors. Licensee MDPIThis research was funded by Community of Madrid projects ADITIMAT-CM -S2018/NMT-4411 and S2018/NMT-4381-MAT4.0-CM.C; Spanish Ministry of Science and Innovation projects RTI2018-096391-B-C31, RTI2018-095856-B-C21 and PTA2015-10497-I; and Ayudas a la Movilidad PDIURJC 2018 and 2019.
NO Ministerio de Ciencia e Innovación (MICINN) / FEDER
NO Ministerio de Ciencia e Innovación (MICINN)
NO Comunidad de Madrid
NO Universidad Rey Juan Carlos (URJC)
DS Docta Complutense
RD 26 dic 2025