TY - JOUR AU - Barros-Miñones, Lucía AU - Martín De Saavedra Álvarez De Uribarri, María Dolores AU - Perez-Alvarez, Sergio AU - Orejana, Lourdes AU - Suquía, Verónica AU - Goñi-Allo, Beatriz AU - Hervias, Isabel AU - López, Manuela AU - Jordan, Joaquin AU - Aguirre, Norberto AU - Puerta, Elena PY - 2013 DO - 10.1016/j.bbadis.2013.02.002 SN - 0925-4439 UR - https://hdl.handle.net/20.500.14352/92821 T2 - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease AB - Phosphodiesterase 5 (PDE5) inhibitors have recently been reported to exert beneficial effects against ischemia–reperfusion injury in several organs but their neuroprotective effects in brain stroke models are scarce. The present study was undertaken... LA - eng M2 - 705 PB - Elsevier KW - Apoptosis KW - Calpain KW - Cyclin-dependent kinase 5 (cdk5) KW - Excitotoxicity KW - Malonate KW - Sildenafil TI - Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate TY - journal article VL - 1832 ER -