RT Journal Article
T1 Biopolymer-stabilized selenium and selenium‑copper nanoparticles with antioxidant and photoprotective dual functionality
A1 Luque García, José Luis
A1 Anunciacao, Daniela S.
A1 Barbosa, Cintya D. Angeles do E.S.
A1 Carinhanha, Josue
A1 Guimaraes, Ari S.
A1 Oliveria, Woodland de S.
A1 Perez Roldan, Angel
A1 da Silva Neta, Maria de Fatima
A1 da Vega, Amanda G.
AB The development of multifunctional nanomaterials with antioxidant and photoprotective properties offers significant potential for cosmetic and biomedical applications. In this study, selenium (SeNPs) and selenium–copper (SeCuNPs) nanoparticles were synthesized via chemical reduction using chitosan (CHI) and polyvinyl alcohol (PVA) as stabilizers. Transmission electron microscopy confirmed a spherical morphology, with mean sizes of 85.4 ± 20.2 nm (SeNPs_CHI) and 76.2 ± 12.0 nm (SeCuNPs_CHI), and significantly smaller sizes for PVA-stabilized formulations (34.3 ± 4.0 nm and 32.5 ± 5.8 nm, respectively). X-ray photoelectron spectroscopy (XPS) confirmed the presence of elemental selenium (Se0) and copper (Cu0) in the hybrid nanoparticles. All formulations exhibited potent antioxidant capacity, as demonstrated by ABTS●+, DPPH●, and FRAP assays, outperforming classical standards including Trolox®, ascorbic acid, and quercetin. In vitro sun protection factor (SPF) values were significantly higher than that of the commercial UV filter 2-hydroxy-4-methoxybenzophenone (BZF-3), particularly for SeCuNPs_PVA. Additionally, the nanoparticles displayed excellent photostability under simulated solar irradiation, maintaining or improving SPF over time. These findings highlight the potential of selenium-based nanoparticles, especially hybrid SeCuNPs, as multifunctional agents with strong antioxidant and photoprotective activity, offering a promising platform for the development of next-generation dermocosmetic and biotechnological products.
PB Elsevier
YR 2026
FD 2026-01-31
LK https://hdl.handle.net/20.500.14352/133454
UL https://hdl.handle.net/20.500.14352/133454
LA eng
NO Neta, Maria De Fatima C. Da Silva, et al. «Biopolymer-Stabilized Selenium and Selenium‑copper Nanoparticles with Antioxidant and Photoprotective Dual Functionality». Inorganic Chemistry Communications, vol. 186, abril de 2026, p. 116273. DOI.org (Crossref), https://doi.org/10.1016/j.inoche.2026.116273.
NO Ministerio de Ciencia, Innovación y Universidades
NO Fundação de Amparo à Pesquisa do Estado de Alagoas
NO Conselho Nacional de Desenvolvimento Científico e Tecnológico
NO Universidade Federal de Alagoas
NO Ministério da Educação Brasil
DS Docta Complutense
RD 21 mar 2026