TY - JOUR AU - García-Ortiz, Almudena AU - Martín-Cofreces, Noa B. AU - Ibiza, Sales AU - Ortega, Ángel AU - Izquierdo-Álvarez, Alicia AU - Trullo, Antonio AU - Victor, Víctor M. AU - Calvo, Enrique AU - Sot, Begoña AU - Martínez Ruiz, Antonio AU - Jesús Vázquez AU - Francisco Sánchez-Madrid AU - Juan M. Serrador AU - Laura Machesky PY - 2017 DO - 10.1371/journal.pbio.2000653 SN - 1545-7885 UR - https://hdl.handle.net/20.500.14352/103012 T2 - Plos Biology AB - The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase... LA - eng TI - eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1 TY - journal article VL - 15 ER -