TY - JOUR AU - Villegas Esguevillas, Marta AU - Suhan, Cho AU - Vera Zambrano, Alba AU - Kwon, Jae Won AU - Barreira, Bianca AU - Telli, Göcken AU - Navarro Dorado, Jorge AU - Morales Cano, Daniel AU - Olaiz Navarro, Beatriz De AU - Moreno Gutiérrez, Laura AU - Greenwood, Iain AU - Pérez Vizcaíno, Francisco AU - Kim, Sung Joon AU - Climent Flórez, Belén AU - Cogolludo Torralba, Ángel Luis PY - 2023 DO - 10.1016/j.biopha.2023.114952 SN - 0753-3322 UR - https://hdl.handle.net/20.500.14352/108774 T2 - Biomedicine & Pharmacotherapy AB - KV7 channels exert a pivotal role regulating vascular tone in several vascular beds. In this context, KV7 channel agonists represent an attractive strategy for the treatment of pulmonary arterial hypertension (PAH). Therefore, in this study, we have... LA - eng M2 - 1 PB - Elsevier KW - KV7 channel activator KW - Pulmonary hypertension KW - Vasodilation KW - KCNQ KW - Potassium channels KW - KCNE4 regulatory subunit TI - The novel KV7 channel activator URO-K10 exerts enhanced pulmonary vascular effects independent of the KCNE4 regulatory subunit TY - journal article VL - 164 ER -