RT Journal Article T1 Integrated Affinity Biosensing Platforms on Screen-Printed Electrodes Electrografted with Diazonium Salts A1 Yáñez Sedeño, Paloma A1 Campuzano Ruiz, Susana A1 Pingarrón Carrazón, José Manuel AB Adequate selection of the electrode surface and the strategies for its modification to enable subsequent immobilization of biomolecules and/or nanomaterials integration play a major role in the performance of electrochemical affinity biosensors. Because of the simplicity, rapidity and versatility, electrografting using diazonium salt reduction is among the most currently used functionalization methods to provide the attachment of an organic layer to a conductive substrate. This particular chemistry has demonstrated to be a powerful tool to covalently immobilize in a stable and reproducible way a wide range of biomolecules or nanomaterials onto different electrode surfaces. Considering the great progress and interesting features arisen in the last years, this paper outlines the potential of diazonium chemistry to prepare single or multianalyte electrochemical affinity biosensors on screen-printed electrodes (SPEs) and points out the existing challenges and future directions in this field. PB MDPI SN 1424-8220 YR 2018 FD 2018-02-24 LK https://hdl.handle.net/20.500.14352/12647 UL https://hdl.handle.net/20.500.14352/12647 LA eng NO Ministerio de Economía y Competitividad (MINECO) NO Comunidad de Madrid DS Docta Complutense RD 8 may 2024