RT Journal Article T1 What Electrochemical Biosensors Can Do for Forensic Science? Unique Features and Applications A1 Yáñez Sedeño, Paloma A1 Agüí Chicharro, María Lourdes A1 Campuzano Ruiz, Susana A1 Pingarrón Carrazón, José Manuel AB This article critically discusses the latest advances in the use of voltammetric, amperometric, potentiometric, and impedimetric biosensors for forensic analysis. Highlighted examples that show the advantages of these tools to develop methods capable of detecting very small concentrations of analytes and provide selective determinations through analytical responses, without significant interferences from other components of the samples, are presented and discussed, thus stressing the great versatility and utility of electrochemical biosensors in this growing research field. To illustrate this, the determination of substances with forensic relevance by using electrochemical biosensors reported in the last five years (2015–2019) are reviewed. The different configurations of enzyme or affinity biosensors used to solve analytical problems related to forensic practice, with special attention to applications in complex samples, are considered. Main prospects, challenges to focus, such as the fabrication of devices for rapid analysis of target analytes directly on-site at the crime scene, or their widespread use and successful applications to complex samples of interest in forensic analysis, and future efforts, are also briefly discussed. PB MDPI SN 2079-6374 YR 2019 FD 2019-10-29 LK https://hdl.handle.net/20.500.14352/8235 UL https://hdl.handle.net/20.500.14352/8235 LA eng NO Ministerio de Economía y Competitividad (MINECO) NO Ministerio de Ciencia e Innovación (MICINN) NO Comunidad de Madrid DS Docta Complutense RD 15 may 2024