RT Journal Article
T1 Formation of peptide bonds from metastable versus crystalline phase: implications for the origin of life
A1 Viedma Molero, Cristóbal
AB Formation of peptide bonds was attempted by thermal activation of dry amino acids fromaqueous solution that simulated prebiotic evaporative environments. The evaporation trend of aminoacids solutions shows a bifurcation and can lead to either a crystalline phase (near equilibrium) or ametastable non-crystalline phase (far from equilibrium). Only amino acids in this metastable phaseare able to form peptide bonds by thermal activation at temperatures that are generated by solarradiation today. We suggest that this metastable phase is the ideal initial material to trigger aminoacid assemblage with protein-like structure because provide the driving force (supersaturation) foran intense interaction between monomers of different amino acids and allows activation of thesemonomers in plausible prebiotic conditions.
PB Springer Science Business Media
SN 0169-6149
YR 2000
FD 2000
LK https://hdl.handle.net/20.500.14352/57567
UL https://hdl.handle.net/20.500.14352/57567
LA eng
DS Docta Complutense
RD 9 may 2025