TY - JOUR AU - Benito León, María AU - Serrano-López, Julia AU - Llorente-Sáez, Celia AU - Arribas Blázquez, Marina AU - Olivos Ore, Luis Alcides AU - Pravata, Veronica AU - Pérez Sen, Raquel AU - García Delicado, Esmerilda AU - Drukker, Micha AU - Rodríguez Artalejo, Antonio AU - Cappello, Silvia AU - Gómez Villafuertes, María Rosa AU - Ortega De La O, Felipe PY - 2026 DO - 10.1016/j.neuropharm.2025.110784 SN - 0028-3908 UR - https://hdl.handle.net/20.500.14352/128602 T2 - Neuropharmacology AB - The human neocortex represents a crucial evolutionary advance, the formation of which requires the tight and precise orchestration of both intracellular and extracellular signals. Structures grown in three-dimensional cultures, specifically... LA - eng M2 - 1 PB - Elsevier KW - Human cortical formation KW - Cerebral organoids KW - Purinergic signaling KW - P2X receptors KW - Neural stem cells TI - P2X purinergic receptors are required for correct cortical development in human brain organoids TY - journal article VL - 284 ER -