RT Journal Article
T1 Ecological Niche Modeling of Francisella tularensis Subspecies and Clades in the United States
A1 Nakazawa, Yoshinori
A1 Williams, Richard Alexander John
A1 Peterson, Townsend
A1 Mead, Paul
A1 Kugelar, Kiersten
A1 Peterson, Jeannine
AB Two subspecies of Francisella tularensis are recognized: F. tularensis subsp. tularensis (type A) and F. tularensis subsp. holartica (type B). Type A has been subdivided further into A1a, A1b, and A2, which differ geographically and clinically. The aim of this work was to determine whether or not differences among subspecies and clades translate into distinct ecological niches. We used 223 isolates from humans and wildlife representing all six genotypes (type A, B, A1, A2, A1a, or A1b). Ecological-niche models were built independently for each genotype, using the genetic algorithm for ruleset prediction. The resulting models were compared using a non-parametric multivariate analysis-of-variance method. A1 and A2 are ecologically distinct, supporting the previously observed geographic division, whereas ecological niches for types A and B overlapped notably but A1a and A1b displayed no appreciable differences in their ecological niches.
PB American Society of Tropical Medicine and Hygiene
SN 0002-9637
YR 2010
FD 2010
LK https://hdl.handle.net/20.500.14352/100365
UL https://hdl.handle.net/20.500.14352/100365
LA eng
NO Nakazawa Y, Williams RA, Peterson AT, Mead PS, Kugeler KJ, Petersen JM. Ecological niche modeling of Francisella tularensis subspecies and clades in the United States. The American journal of tropical medicine and hygiene. 2010 May;82(5):912.
NO U.S. Department of Defense
NO Centers for Disease Control and Prevention (U.S.A)
NO Microsoft Research
DS Docta Complutense
RD 6 abr 2025