%0 Generic %A Pérez Carrasco, María Jesús %A Sánchez Ramos, Celia %A Moral Martínez, M.I. %A Puell Marín, María Cinta %A Langa Moraga, Antonio %T Effect of Mesopic/Scotopic Luminance on Pupil Diameter and Anisocoria in Drivers Over 65 Years of Age %D 2005 %U https://hdl.handle.net/20.500.14352/106922 %X Purpose: To evaluate the changes produced in pupil diameter and anisocoria in mesopic and scotopic conditions in subjects over the age of 65 years.Methods: A prospective evaluation was performed of pupil diameter in 45 motor car drivers aged 65 to 80 years (69±6 years). Measurements were made using an infrared, binocular pupillometer P2000 (Procyon Instruments Ltd) at 3 luminance levels: 0.04 lux (scotopic), 0.4 lux (low mesopic) and 4 lux (high mesopic). For each measurement, 10 photographs of both eyes are automatically taken by the instrument. Results: In scotopic conditions, mean pupil sizes were RE 5.37±1.1 mm, LE 5.29±1 mm. When the luminance level was increased to 0.4 lux (low mesopic conditions) mioses of 18% and 17%, respectively for the right and left eyes, were observed, resulting in pupil diameters of RE 4.55±0.83 mm, LE 4.51±0.78 mm. In high mesopic conditions (4 lux), pupil diameters were RE 3.47±0.60 mm, LE 3.41±0.89 mm, corresponding to mioses from the previous luminance level of 28% and 29%, respectively. The diferences in pupil diameter among the three luminance levels were significant. No diferences attributable to the luminance level were detected between each eye. The degrees ofanisocoria observed were 5.77%, 5.78% and 5.77% in scotopic, low and high mesopic conditions, respectively. No significant diferences in scotopic/mesopic pupil sizes were revealed when the population was divided into three (15–year) age groups, or according to sex.Conclusions: At scotopic and mesopic luminance levels, drivers over 65 years show significant diferences in pupil diameter but no changes in anisocoria. %~