RT Journal Article T1 The challenge of well-being and quality of life: A meta-analysis of psychological interventions in schizophrenia A1 Valiente Ots, M. Carmen A1 Espinosa, Regina A1 Trucharte Martínez, Almudena A1 Nieto, Juan A1 Martínez Prado, Leticia AB Well-being is a critical outcome in the recovery from psychosis and the prevention of symptoms. Previous reviewsof the effectiveness of psychological interventions have focused on psychotic symptoms and general psychopathology,not recognising well-being as an essential outcome. This study conducted a meta-analysis of theeffects of psychological interventions on the well-being and quality of life (QoL) of people with schizophreniaand analysed some criticalmoderating factors. A systematic literature searchwas conducted yielding 12986 publishedreports, 2043 ofwhichwere clinical trials. After a detailed review, 36 articleswere included in the analyses.Measures of related concepts,well-being and quality of life were included in the present meta-analysis to reflectthe current state of the literature and to ensure the representativeness of RCTs that have evaluated the effect ofpsychological interventions on the extent to which people with schizophrenia experience a good life. Our findingsreflect a significant, small, treatment effect on the outcomes ofwell-being. Subgroup analysis also suggesteda significant moderating effectwhen the primary aimof the intervention waswell-being. These findings suggestthat symptomor functional improvement does not necessarily lead to an improvement inwell-being and wouldimply the need to focus specifically on those.We recommend psychological interventions that target well-beingas a complementary strategy in mental health promotion and treatment. In addition, we stress the need to includewell-being outcome measure in RCT as well as to clearly identify the different domains of well-beingbeing measured. PB Elsevier SN 0920-9964 YR 2019 FD 2019-03-01 LK https://hdl.handle.net/20.500.14352/116181 UL https://hdl.handle.net/20.500.14352/116181 LA eng NO Valiente, C., Espinosa, R., Trucharte, A., Nieto, J., & Martínez-Prado, L. (2019). The challenge of well-being and quality of life: A meta-analysis of psychological interventions in schizophrenia. Schizophrenia Research, 208, 16-24. https://doi.org/10.1016/j.schres.2019.01.040 NO Ministerio de Ciencia e Innovación (España) DS Docta Complutense RD 14 dic 2025