RT Journal Article
T1 Lifestyle interventions for the prevention and treatment of hypertension
A1 Valenzuela, Pedro L.
A1 Carrera-Bastos, Pedro
A1 González Gálvez, Beatriz
A1 Ruiz-Hurtado, Gema
A1 Ordovas, José M.
A1 Ruilope, Luis M.
A1 Lucia, Alejandro
AB Hypertension affects approximately one third of the world's adult population and is a major cause of premature death despite considerable advances in pharmacological treatments. Growing evidence supports the use of lifestyle interventions for the prevention and adjuvant treatment of hypertension. In this Review, we provide a summary of the epidemiological research supporting the preventive and antihypertensive effects of major lifestyle interventions (regular physical exercise, body weight management and healthy dietary patterns), as well as other less traditional recommendations such as stress management and the promotion of adequate sleep patterns coupled with circadian entrainment. We also discuss the physiological mechanisms underlying the beneficial effects of these lifestyle interventions on hypertension, which include not only the prevention of traditional risk factors (such as obesity and insulin resistance) and improvements in vascular health through an improved redox and inflammatory status, but also reduced sympathetic overactivation and non-traditional mechanisms such as increased secretion of myokines.
SN 1759-5002
SN 1759-5010
YR 2020
FD 2020-10-09
LK https://hdl.handle.net/20.500.14352/104850
UL https://hdl.handle.net/20.500.14352/104850
LA eng
DS Docta Complutense
RD 5 abr 2025