RT Journal Article T1 National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020 A1 Miguel Díez, Javier De A1 López De Andrés, Ana Isabel A1 Jiménez García, Rodrigo A1 Miguel Yanes, José María De A1 Hernández Barrera, Valentín A1 Carabantes Alarcón, David A1 Zamorano León, José Javier A1 Noriega, Concepción AB Background: To describe trends in the prevalence of depression in men and women with COPD hospitalized in Spain (2016–2020).Methods: We used a nationwide discharge database to select all patients ≥35 years with COPD.Results: The prevalence of depression was 3.54-times higher in women with COPD than in men (OR 3.54; 95%CI 3.48–3.6). It decreased significantly between 2016 and 2020, although the reduction was only significant in women (12.27% in 2016 vs. 10.56% in 2020). Older age, comorbidity and the most recent years of hospital admission were associated with lower prevalence of depression in both men and women, while obesity, obstructive sleep apnea (OSA) and use of oxygen prior to admission were risk factors. In-hospital mortality (IHM) increased significantly over time. Older age, comorbidity, the use of oxygen prior to admission and having been hospitalized in 2020 increased the risk of IHM. Female sex was associated with a lower IHM in patients with depression and COPD.Conclusions: The prevalence of depression has decreased over time in women with COPD while it has not changed significantly in men with this disease. IHM increased over time both in men and women with COPD and depression, with higher prevalence in the former. PB MDPI SN 2077-0383 YR 2022 FD 2022-10-27 LK https://hdl.handle.net/20.500.14352/72280 UL https://hdl.handle.net/20.500.14352/72280 LA eng NO Miguel Díez, J., López De Andrés, A. I., Jiménez García, R. et al. «National Trends in Prevalence of Depression in Men and Women with Chronic Obstructive Pulmonary Disease Hospitalized in Spain, 2016–2020». Journal of Clinical Medicine, vol. 11, n.o 21, octubre de 2022, p. 6337. DOI.org (Crossref), https://doi.org/10.3390/jcm11216337. NO Comunidad de Madrid NO Universidad Complutense de Madrid NO Universidad Complutense de Madrid: Grupo de Investigación en Epidemiología de las Enfermedades Crónicas de Alta Prevalencia en España NO Sociedad Española de Neumología y Cirugía de Tórax DS Docta Complutense RD 5 abr 2025