RT Journal Article T1 Stabilization in early adult-onset myopia with corneal refractive therapy A1 González Méijome, José Manuel A1 Carracedo Rodríguez, Juan Gonzalo A1 Lopes Ferreira, Daniela P. A1 Faria Ribeiro, Migue A. A1 Peixoto de Matos, Sofía C. A1 Queiros, Antonio AB Purpose: To describe the stabilization of early adult-onset myopia in three university students after initiating orthokeratology treatment with corneal refractive therapy contact lenses.Methods: Three Caucasian early adult-onset progressing myopic subjects (1 male, 2 females) were fitted with corneal refractive therapy lenses to correct myopia between −1.50 and −2.50 D of sphere using Paragon CRT (Paragon Vision Sciences, Mesa, AZ) lenses for overnight orthokeratology. The pre-treatment refractive history from 2005 as well as refraction and axial length after treatment onset are reported over a period of 3 years between December 2009 and January 2013 with an additional year of follow-up after treatment discontinuation (January–December 2013). The peripheral refractive patterns and topographic changes are also reported individually.Results: Treatment was successful in all three subjects achieving uncorrected visual acuity of 20/20 or better monocularly. During a period of 3 years of follow-up the subjects did not experience progression in their refractive error, nor in their axial length (measured during the last 2 years of treatment and 1 year after discontinuation). Furthermore, the subjects recovered to their baseline refraction and did not progressed further over the following year after lens wear discontinuation.Conclusions: We cannot attribute a causative effect to the orthokeratology treatment alone as underlying mechanism for myopia stabilization in this 3 patients. However, the present report points to the possibility of stabilization of early adult-onset myopia progression in young adults using corneal refractive therapy treatment. PB Elsevier SN 1367-0484 YR 2016 FD 2016-02 LK https://hdl.handle.net/20.500.14352/23417 UL https://hdl.handle.net/20.500.14352/23417 LA eng NO Received 22 December 2014, Revised 2 June 2015, Accepted 30 June 2015, Available online 15 July 2015. NO FEDER. COMPETE Program NO Portuguese Foundation for Science and Technology (FCT) DS Docta Complutense RD 12 abr 2025