RT Journal Article
T1 First detection of Anaplasma phagocytophilum and Babesia divergens and high infection rates of Anaplasma marginale and Babesia bigemina in cattle in extensive grazing systems of Central Spain
A1 Calleja‐Bueno, Lydia
A1 Sainz Rodríguez, Ángel
A1 García-Sancho Téllez, Mercedes Guadalupe
A1 González Martín, Juan Vicente
A1 Díaz-Regañón Fernández, David Rafael
A1 Rodríguez Franco, Fernando
A1 Agulla Pérez, Beatriz
A1 Tormo, Bárbara
A1 Villaescusa Fernández, Alejandra
AB Bovine vector-borne diseases have a considerable economic impact worldwide and affect health of humans and animals. However, different aspects of their epidemiology and their pathogenesis remain unclear. Despite the frequent description of clinical cases reported by practitioners attending cattle from Madrid, Central Spain, molecular prevalence of Anaplasma spp. and Babesia spp. has not been described. The aim of this study was to assess the positivity rate of A. phagocytophilum, A. marginale, A. centrale, B. bigemina and B. divergens in livestock of this area and to evaluate the existence of associations between these pathogens and haematological, biochemical and epidemiological data. Babesia divergens and A. phagocytophilum were detected for the first time in cattle from Madrid. Their positivity percentages were low (2.2% ± 1.4% and 1.8% ± 1.2%, respectively), but this description is of special interest, as these agents are potentially zoonotic. Both agents were found in areas of higher altitude and relative humidity and lower temperature. The detection of ticks in livestock during the moment of sampling was confirmed as a risk factor for these infections. Anaplasma marginale showed the highest molecular infection rate (30% ± 4.1%) in this study, followed by B. bigemina (21.9% ± 3.7%). Higher positivity rates of A. marginale and B. bigemina were found in the areas of mountain climate and warm-summer continental Mediterranean climate. The use of ectoparasiticide treatment was found as a risk factor for infection by A. marginale and B. bigemina. This finding could lead to reconsider the ectoparasiticide protocols that are used nowadays. Grazing on pastures with domestic or wild ruminants and the presence of wild carnivores were associated with higher rates of infection by these four agents and coinfections were frequently found.
PB Wiley
SN 1865-1674
SN 1865-1682
YR 2021
FD 2021-11-18
LK https://hdl.handle.net/20.500.14352/113990
UL https://hdl.handle.net/20.500.14352/113990
LA eng
NO Calleja-Bueno L, Sainz Á, García-Sancho M, González-Martín JV, Díaz-Regañón D, Rodríguez-Franco F, Agulla B, Tormo B, Villaescusa A. First detection of Anaplasma phagocytophilum and Babesia divergens and high infection rates of Anaplasma marginale and Babesia bigemina in cattle in extensive grazing systems of Central Spain. Transbound Emerg Dis. 2022 Jul;69(4):e1090-e1100. https://doi.org/10.1111/tbed.14394
DS Docta Complutense
RD 10 abr 2025