RT Journal Article
T1 Feasibility of optical quality analysis system for the objetctive assessment of accommodation insufficiency: a phase 1 study
A1 López Artero, Esther
A1 Garzón Jiménez, Nuria
A1 Rodríguez Vallejo, Manuel
A1 García Montero, María
AB Purpose: To assess differences in a new objective metric obtained with a double-pass technique between a group with accommodation insufficiency (AI) and a control group  and to explore the diagnostic capabilities of this new tool in comparison to  conventional procedures.Methods: Retrospective cross-sectional case-control phase 1 study. Two groups age  ranging from 8 to 18 years were recruitment: AI and control group. The diagnostic  criterion of AI was based on monocular accommodative amplitude (AA) 2 D below  Hofstetter’s calculation for minimum AA and monocular accommodative facility (MAF)  failing with minus lens and cut-off at ≤ 6 cycles per minute. Accommodative response  with a double pass device (HD Analyzer, Visiometrics) was measured, performing an  evaluation from +1.00 D to −3.50D (−0.5D steps), offering the width of the profile  at 50% (WP) in minutes of arc.Results: Differences were found between groups for the AA, MAF and MEM retinoscopy (p < 0.0001, p < 0.001, p = 0.037). The discriminative capacity of MEM retinoscopy  for AI diagnosis was significant and the cut-off that maximized the sensitivity and  specificity was > 0.5 D. Considering WP 50% in different points, the discriminative  AI diagnosis capacities for the points of 2.0 D and 2.50 D were significant (ROC-AUC  0.78; p = 0.03 and p = 0.02).Conclusions: Double-pass system metric differed between patients with AI and control  group, therefore the aim of a Phase I study was achieved. Further steps with higher  sample sizes are required to evidence if the system really provides any advantage  versus conventional methods in the diagnosis of AI.
PB Spanish General Council of Optometrists; Elsevier
SN 1888-4296
YR 2020
FD 2020
LK https://hdl.handle.net/20.500.14352/6427
UL https://hdl.handle.net/20.500.14352/6427
LA eng
NO Recibido: 11 enero 2020; Aceptado: 29 junio 2020
DS Docta Complutense
RD 1 ago 2024