%0 Generic
%A Rawat, Amit
%A Regueiro González-Barros, José Ramón
%A Briones Contreras, Alejandro
%A Singh, Surjit
%T Skewed TCR alpha, but not beta, gene rearrangements and lymphoma associated with a pathogenic TRAC variant
%D 2021
%U https://hdl.handle.net/20.500.14352/106044
%X We report a non-consanguineous family from North-west India in which 3 siblings succumbed to a rare variant of combined immunodeficiency. All three had similar clinical and immunological profiles. However, the youngest child also developed Non-Hodgkin lymphoma in infancy. Genetic analysis revealed a previously reported variant in the T cell receptor alpha constant (TRAC) gene.
%~