RT Journal Article
T1 Iron Oxide Nanoparticles: An Alternative for Positive Contrast in Magnetic Resonance Imaging
A1 Fernández Barahona, Irene
A1 Muñoz-Hernando, María
A1 Ruiz Cabello, Jesús
A1 Herranz, Fernando
A1 Pellico, Juan
AB Iron oxide nanoparticles have been extensively utilised as negative (T2) contrast agents in magnetic resonance imaging. In the past few years, researchers have also exploited their application as positive (T1) contrast agents to overcome the limitation of traditional Gd3+ contrast agents. To provide T1 contrast, these particles must present certain physicochemical properties with control over the size, morphology and surface of the particles. In this review, we summarise the reported T1 iron oxide nanoparticles and critically revise their properties, synthetic protocols and application, not only in MRI but also in multimodal imaging. In addition, we briefly summarise the most important nanoparticulate Gd and Mn agents to evaluate whether T1 iron oxide nanoparticles can reach Gd/Mn contrast capabilities.
PB MDPI
SN 2304-6740
YR 2020
FD 2020-04-10
LK https://hdl.handle.net/20.500.14352/8321
UL https://hdl.handle.net/20.500.14352/8321
LA eng
NO Ministerio de Economía y Competitividad (MINECO)
NO Ministerio de Ciencia e Innovación (MICINN)
NO Unidad de Excelencia Maria de Maeztu
NO Gobierno Vasco
DS Docta Complutense
RD 10 abr 2025