RT Journal Article
T1 Folic acid deficiency and vision: a review
A1 Sijilmassi, Ouafa
AB Folic acid (FA), also termed folate, is an essential vitamin for health at all ages since it participates in the biosynthesis of nucleotides, amino acids, neurotransmitters, and certain vitamins. It is therefore crucial for rapidly growing tissues such as those of the fetus. It is becoming clear that FA deficiency and impaired folate pathways are implicated in many diseases of both early life and old age. FA can be transported into the cell by the folate receptor, the reduced folate transporter, and proton-coupled folate transporter. Folate transport proteins are present in certain eye tissues, which explains why FA plays an important role in eye development. The purpose of this literature review is to investigate the evidence relating FA deficiency to eye diseases.
PB Springer
SN 0721-832X
YR 2019
FD 2019-03-27
LK https://hdl.handle.net/20.500.14352/121296
UL https://hdl.handle.net/20.500.14352/121296
LA eng
NO Sijilmassi, O. Folic acid deficiency and vision: a review. Graefes Arch Clin Exp Ophthalmol 257, 1573–1580 (2019). https://doi.org/10.1007/s00417-019-04304-3
NO Received: 27 November 2018 ; Revised: 10 February 2019 ; Accepted: 20 March 2019 ; Published: 27 March 2019 ; Issue Date: 05 August 2019
NO Universidad Complutense de Madrid
NO Banco Santander
NO Ministerio de Economía y Competitivad de España
DS Docta Complutense
RD 19 dic 2025