TY - JOUR AU - Del Campo, Rosa AU - Cafini, Fabio AU - Morosini, María Isabel AU - Fenoll, Asunción AU - Liñares, Josefina AU - Alou Cervera, Luis AU - Sevillano Fernández, David AU - Cantón Moreno, Rafael María AU - Prieto Prieto, José AU - Baquero, Fernando PY - 2006 DO - 10.1093/jac/dkl083 SN - 0305-7453 UR - https://hdl.handle.net/20.500.14352/107170 T2 - Journal of Antimicrobial Chemotherapy AB - Objectives: High-level penicillin resistance in Streptococcus pneumoniae requires extensive re-modulation of the penicillin-binding proteins (PBPs), and murM gene function is also required for the expression of resistance. In this work, we determined... LA - eng M2 - 983 PB - Oxford University Press KW - resistance KW - clones KW - mutations KW - penicillin-binding proteins TI - Combinations of PBPs and MurM protein variants in early and contemporary high-level penicillin-resistant Streptococcus pneumoniae isolates in Spain TY - journal article VL - 57 ER -