RT Journal Article
T1 Circadian rhythms in thrombosis and atherothrombotic events
A1 Peñaloza Martínez, Eduardo
A1 Moreno Muñoz, Guillermo
A1 Aroca Crevillén, Alejandra
A1 Huertas, Sergio
A1 Vicent, Lourdes
A1 Rosillo, Nicolás
A1 Hidalgo, Andrés
A1 Bueno Zamora, Héctor José
AB Biological circadian rhythms in living organisms are regulated by molecular clocks. Several of these clocks are present in blood vessels, peripheral tissues, and immune cells. There is strong evidence linking dysregulation of circadian rhythms to the development of cardiovascular disease. Dysregulation of circadian rhythms is believed to activate inflammatory processes at specific times of day, leading to an increased risk of thrombosis and atherosclerosis progression. Research into circadian clock genes and molecular networks has the potential to identify therapeutic targets to reduce cardiovascular risk. In this review, we summarize the evidence linking circadian rhythms to thrombosis and atherothrombotic events and discuss potential therapeutic implications.
PB IMR Press
SN 2768-6701
YR 2022
FD 2022-02-11
LK https://hdl.handle.net/20.500.14352/109565
UL https://hdl.handle.net/20.500.14352/109565
LA eng
NO Peñaloza-Martínez E, Moreno G, Aroca-Crevillén A, Huertas S, Vicent L, Rosillo N, et al. Circadian rhythms in thrombosis and atherothrombotic events. Frontiers in bioscience (Landmark edition). NLM (Medline); 2022;27(2):51.
DS Docta Complutense
RD 10 abr 2025