RT Journal Article
T1 Differences in the Outcome of Patients with COPD according to Body Mass Index
A1 Ji, Zichen
A1 Miguel Díez, Javier De
A1 Castro Riera, Christian Reynaldo
A1 Bellón Cano, José María
A1 Gallo González, Virginia
A1 Girón Matute, Walther Iván
A1 Jiménez García, Rodrigo
A1 López De Andrés, Ana Isabel
A1 Moya Álvarez, Virginia
A1 Puente Maestu, Luis
A1 Hernández Vázquez, Julio
AB Background: In chronic obstructive pulmonary disease (COPD), the “obesity paradox” is a phenomenon without a clear cause. The objective is to analyze the complications of COPD patients according to their body mass index (BMI). Methods: An observational study with a six-year prospective follow-up of 273 COPD patients who attended a spirometry test in 2011. Survival and acute events were analyzed according to the BMI quartiles. Results: A total of 273 patients were included. BMI quartiles were ≤24.23; 24.24–27.69; 27.70–31.25; ≥31.26. During the follow-up, 93 patients died. No differences were found in exacerbations, pneumonia, emergency visits, hospital admissions or income in a critical unit. Survival was lower in the quartile 1 of BMI with respect to each of the 2–4 quartiles (p-value 0.019, 0.013, and 0.004, respectively). Advanced age (hazard ratio, HR 1.06; 95% confidence interval, CI 1.03–1.09), low pulmonary function (HR 0.93; 95% CI 0.86–0.99), exacerbator with chronic bronchitis phenotype (HR 1.76; 95% CI 1.01–3.06), high Charlson (HR 1.32, 95% CI 1.18–1.49), and the quartile 1 of BMI (HR 1.99, 95% CI 1.08–3.69) were identified as risk factors independently associated with mortality. Conclusions: In COPD, low BMI conditions a lower survival, although not for having more acute events.
PB MDPI
SN 2077-0383
YR 2020
FD 2020-03-05
LK https://hdl.handle.net/20.500.14352/8202
UL https://hdl.handle.net/20.500.14352/8202
LA eng
NO Ji, Z., Miguel Díez, J., Castro Riera, C. R. et al. «Differences in the Outcome of Patients with COPD According to Body Mass Index». Journal of Clinical Medicine, vol. 9, n.o 3, marzo de 2020, p. 710. DOI.org (Crossref), https://doi.org/10.3390/jcm9030710.
DS Docta Complutense
RD 9 abr 2025