RT Book, Section
T1 Suprachoroidal MIGS Devices
A1 García Feijoo, Julián
A1 Martínez De La Casa Fernández-Borrella, José María
A1 Perucho González, Lucía
A2 Barton, Keith
A2 Chelvin, C. A. Sng
AB The suprachoroidal outflow pathway has the potential to reduce intraocular pressure (IOP) significantly but has been associated with sight-threatening complications including severe and prolonged hypotony. Historically, suprachoroidal devices have been implanted ab externo requiring a conjunctival peritomy and scleral flap dissection. Additionally, the long-term efficacy of previous attempts to harness this space has been disappointing due to occlusion of implanted devices by fibrosis in the suprachoroidal space. More recently, there have been a number of suprachoroidal devices that are injected ab interno., including the CyPass Micro-Stent (Alcon Laboratories Inc., Fortworth, Texas, USA), the iStent Supra (Glaukos Corporation, San Clemente, CA, USA) and the MINIject (iSTAR Medical Isnes, Belgium). These have utilized a clear corneal entry, thereby sparing the conjunctiva. Early results with these ab-interno devices showed safety and efficacy in IOP-lowering that is similar to Schlemm’s canal minimally invasive glaucoma surgery devices and procedures. Despite the ab-interno approach, their long-term efficacy also seems to be limited by fibrosis. In addition, the first commercially available ab-interno suprachoroidal device, the CyPass Micro-Stent, has been voluntarily withdrawn globally by the manufacturer in August 2018, after 5-year follow-up data demonstrated a higher level of endothelial cell loss with the device than in controls. The iStent Supra and MINIject are not yet available commercially.
PB Springer
SN 978-981-15-5631-9 ; 978-981-15-5632-6 (online)
YR 2020
FD 2020-11-04
LK https://hdl.handle.net/20.500.14352/8778
UL https://hdl.handle.net/20.500.14352/8778
LA eng
NO Garcia-Feijoo, J., Martínez De La Casa Fernández-Borrella, J. M., Perucho González, L. «Suprachoroidal MIGS Devices». Minimally Invasive Glaucoma Surgery, editado por Chelvin C. A. Sng y Keith Barton, Springer Singapore, 2021, pp. 105-19. DOI.org (Crossref), https://doi.org/10.1007/978-981-15-5632-6_8.
NO Libro publicado en Acceso  Abierto
DS Docta Complutense
RD 9 abr 2025