RT Journal Article T1 Different Effect of Vitamin E or Hydroxytyrosol Supplementation to Sow’s Diet on Oxidative Status and Performances of Weaned Piglets A1 Gómez, Gerardo A1 Laviano, Hernan D. A1 García-Casco, Juan M. A1 Muñoz, María A1 González-Bulnes, Antonio A1 Óvilo, Cristina A1 Rey Muñoz, Ana Isabel A1 López Bote, Clemente José A1 De las Heras Molina, Ana A1 Escudero Portugués, Rosa María AB Different feeding strategies are being applied to sows in order to obtain homogeneous piglets’ weights and improved health status. This study evaluated how the dietary supplementation of vitamin E (VE) (100 mg/kg), hydroxytyrosol (HXT) (1.5 mg/kg) or the combined administration (VE + HXT) given to Iberian sows from day 85 of gestation affected the growth pattern of the piglets and their oxidative status; and quantified what these effects were due to. Dietary VE and HXT improved the oxidative status of sows and piglets. Both VE and HXT modified the growth pattern at birth and performances of the piglets in a different way according to the growing period. Piglets’ performances were positively correlated with plasma VE and negatively with plasma malondialdehyde (MDA) of the sow. However, the highest variation in growth patterns was explained by the colostrum composition. Significant linear equations were observed between piglets’ performances and colostrum saturated (SAT), n-7 monounsaturated fatty acids (C16:1n-7 and C18:1n-7) and different desaturases indices. This study would confirm that VE supplementation to the sow diet could be more adequate than HXT for the improved development during the first weeks of a piglet’s life. The combined administration of both antioxidants would not produce additional positive effects compared to the individual supplementation. PB MDPI SN 2076-3921 YR 2023 FD 2023-07-27 LK https://hdl.handle.net/20.500.14352/101746 UL https://hdl.handle.net/20.500.14352/101746 LA eng NO Gómez, G.; Laviano, H.D.; García-Casco, J.M.; Escudero, R.; Muñoz, M.; Heras-Molina, A.; González-Bulnes, A.; Óvilo, C.; López-Bote, C.; Rey, A.I. Different Effect of Vitamin E or Hydroxytyrosol Supplementation to Sow’s Diet on Oxidative Status and Performances of Weaned Piglets. Antioxidants 2023, 12, 1504. https:// doi.org/10.3390/antiox12081504 NO MINECO NO Agencia estatal de investigación NO IRIAF-Sanchez Romero Carvajal Jabugo NO European Regional Development Fund DS Docta Complutense RD 4 abr 2025