RT Journal Article
T1 Tailoring the Structure of Bioactive Glasses: From the Nanoscale to Macroporous Scaffolds
A1 Vallet Regí, María Dulce Nombre
A1 Salinas Sánchez, Antonio Jesús
A1 Arcos Navarrete, Daniel
AB Bioactive glasses have played a very important role in the development of new materials for bone tissue regeneration. The development of new synthesis and manufacturing methods allows the preparation of bioactive glasses with new chemical compositions, nanoscaled features, customized morphologies, and pore architectures. The composition of glasses can be designed at the atomic-molecular level to ensure bioactivity and beneficial effects including capabilities for enhancing osteogenesis and vascularization or to exert bactericide action. Moreover, the glasses can be prepared as mesoporous bioactive glasses, exhibiting ordered arrangements of nanometric pores. Through the control of the microstructure, glasses can be prepared to achieve suitable interactions with living cells. Finally, the scaffolds obtained with bioactive glasses must display interconnected pores over 100 m to make possible bone cell ingrowths and angiogenesis. In this article, the advances in the field of bioactive glasses through the control of the chemical, nanometer scale, microstructural properties, and architectural features are presented and discussed. A detailed control of these four levels of matter organization will allow optimizing the biological response of bioactive glasses when used in bone tissue regeneration.
PB Wiley
SN 2041-1286
YR 2016
FD 2016-06
LK https://hdl.handle.net/20.500.14352/23164
UL https://hdl.handle.net/20.500.14352/23164
LA eng
NO Vallet Regí, M. D. N., Salinas Sánchez, A. J. & Arcos Navarrete, D. et al. «Tailoring the Structure of Bioactive Glasses: From the Nanoscale to Macroporous Scaffolds». International Journal of Applied Glass Science, vol. 7, n.o 2, junio de 2016, pp. 195-205. DOI.org (Crossref), https://doi.org/10.1111/ijag.12205.
NO RESEARCH ID M-3378-2014 (María Vallet Regí)ORCID 0000-0002-6104-4889 (María Vallet Regí)RESEARCH ID M-3316-2014 (Antonio Salinas Sánchez)ORCID 0000-0002-8408-3389 (Antonio Salinas Sánchez)ORCID 0000-0002-5367-7272 (Daniel Arcos Navarrete)RESEARCHER ID L-6167-2014 (Daniel Arcos Navarrete)
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Ministerio de Economía, Comercio y Empresa (España)
NO Instituto de Salud Carlos III
NO Agening Network of Excellence
DS Docta Complutense
RD 5 abr 2025