RT Journal Article
T1 Does HPV biotype influence the characteristics and evolution of plantar warts?
A1 García Oreja, Sara
A1 Álvaro Afonso, Francisco Javier
A1 Sevillano Fernández, David
A1 García Morales, Esther Alicia
A1 López Moral, Mateo
A1 Lázaro Martínez, José Luis
AB BackgroundFew studies have addressed the relationship of human papillomavirus (HPV) biotypes to patient characteristics and the clinical signs, course, and response to the treatment of plantar warts.ObjectiveAnalyze the HPV types associated with plantar warts and their relationship with warts characteristics, patient characteristics and response to treatment.MethodsA total of 372 patients sampled for hyperkeratosis of a plantar wart were included. Multiplex polymerase chain reaction (PCR) was performed to detect the HPV biotype.ResultsThe prevalence of HPV was 81.2%, and HPV1 was the most prevalent biotype (36.1%). HPV1 was the most prevalent biotype in patients < 70 years old (90.9% in < 10 years), and biotypes 2, 19 and 27 were the most prevalent in patients > 70 years old (p = 0.012). HPV1 was the most frequent in patients with one (39,9%) or two (47.1%) warts and HPV5 (33.3%) in patients with three warts (p < 0.001). Cure, spontaneous resolution, and recurrence were higher in HPV1 (p < 0.001). HPV14 warts healed the fastest (2 months quartile 1–3 (2.0–2.0)), and HPV5 (10.977 (6.0–20.0)) and HPV27 (7.5 (3.0–10.0)) warts (p = 0.033) took the longest to heal.ConclusionsHPV biotype is associated with age and the number of warts and appears to influence the natural history of warts and their response to treatment.
PB Wiley
SN 1756-5383
SN 1756-5391
YR 2024
FD 2024-02-02
LK https://hdl.handle.net/20.500.14352/109826
UL https://hdl.handle.net/20.500.14352/109826
LA eng
NO García-Oreja S, Álvaro-Afonso FJ, Sevillano-Fernández D, García-Morales EA, López-Moral M, Lázaro-Martínez JL. Does HPV biotype influence the characteristics and evolution of plantar warts? J Evid Based Med. 2024 Mar;17(1):10-12.
NO Letter
DS Docta Complutense
RD 5 abr 2025