RT Journal Article
T1 Sarcocystis neurona schizonts-associated encephalitis, chorioretinitis, and myositis in a two-month-old dog simulating toxoplasmosis, and presence of mature sarcocysts in muscles
A1 Dubey, Jitender
A1 Black, Sharon
A1 Verma, Shiv Kumar
A1 Calero Bernal, Rafael
A1 Morris, Erin
A1 Hanson, Margaret
A1 Cooley, Avery James
AB Sarcocystis neurona is an unusual species of the genus Sarcocystis. Opossums (Didelphis virginianus, D. albiventris) are the definitive hosts and several other species, including dogs, cats, marine mammals, and horses are intermediate or aberrant hosts. Sarcocysts are not known to form in aberrant hosts. Sarcocystis neurona causes fatal disease in horses (Equine Protozoal Myeloencephalitis, EPM). There are numerous reports of fatal EPM-like infections in other species, usually with central nervous system signs and associated with the schizont stage of S. neurona. Here, we report fatal disseminated S. neurona infection in a nine-week-old golden retriever dog from Mississippi, USA. Protozoal merozoites were identified in smears of the cerebrospinal fluid. Microscopically, lesions and protozoa were identified in eyes, tongue, heart, liver, intestines, nasal turbinates, skeletal muscle and brain, which reacted intensely with S. neurona polyclonal antibodies. Mature sarcocysts were seen in sections of muscles. These sarcocysts were ultrastructurally similar to those of S. neurona from experimentally infected animals. These data suggest that the dog is another intermediate host for S. neurona. Data suggest that the dog was transplacentally infected.
PB Elsevier
SN 0304-4017
YR 2014
FD 2014
LK https://hdl.handle.net/20.500.14352/100203
UL https://hdl.handle.net/20.500.14352/100203
LA eng
NO Dubey, J. P., Black, S. S., Verma, S. K., Calero-Bernal, R., Morris, E., Hanson, M. A., & Cooley, A. J. (2014). Sarcocystis neurona schizonts-associated encephalitis, chorioretinitis, and myositis in a two-month-old dog simulating toxoplasmosis, and presence of mature sarcocysts in muscles. Veterinary parasitology, 202(3-4), 194–200. https://doi.org/10.1016/j.vetpar.2014.02.055
DS Docta Complutense
RD 18 abr 2025