RT Journal Article
T1 Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
A1 Mukhopadhyay, Debanjan
A1 Arranz Solís, David
A1 Saeij, Jeroen P. J.
AB Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host range, including humans, across the globe. The outcome of infection differs remarkably between hosts, ranging from acute death to sterile infection. These differential disease patterns are strongly influenced by both host- and parasite-specific genetic factors. In this review, we discuss how the clinical outcome of toxoplasmosis varies between hosts and the role of different immune genes and parasite virulence factors, with a special emphasis on Toxoplasma-induced ileitis and encephalitis.
PB Frontiers
YR 2020
FD 2020
LK https://hdl.handle.net/20.500.14352/129374
UL https://hdl.handle.net/20.500.14352/129374
LA eng
NO Mukhopadhyay, D., Arranz-Solís, D., & Saeij, J. P. J. (2020). Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection. Frontiers in cellular and infection microbiology, 10, 580425. https://doi.org/10.3389/fcimb.2020.580425
NO Author ContributionsDM, DA-S, and JPJS have contributed to the conceptualization, writing, and editing of this manuscript. All authors contributed to the article and approved the submitted version
NO National Institutes of Health
NO American Heart Association Post-doctoral fellowship
DS Docta Complutense
RD 31 dic 2025