RT Journal Article T1 Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action A1 Wang, Xiaohui A1 Li, Houpeng A1 Wang, Simeng A1 Martínez Caballero, María Aranzazu A1 Martínez Caballero, Marta A1 Ares Lombán, Irma A1 Martínez Larrañaga, María Rosa A1 Wang, Xu A1 Anadón Navarro, Arturo Ramón A1 Maximiliano Guerra, Jorge Enrique AB Tefluthrin is a Type I pyrethroid insecticide widely used all over the world. Residues of tefluthrin in various agricultural and animal-derived products may be related to potential human health risks. Tefluthrin metabolism in mammals involves hydrolysis of the ester bond to form cyclopropane acid and 4-methylbenzyl alcohol moieties, followed by oxidation. In this review manuscript, we provide crucial information regarding the toxicity of pyrethroids and propose natural antioxidants for amelioration poisoning in humans and animals. We call for the rational use of tefluthrin as an agrochemical product and for greater attention to the residual toxicity caused by tefluthrin in primary and succeeding crops. This greater attention is required given the global use of tefluthrin. PB Taylor & Francis SN 1040-8444 YR 2023 FD 2023 LK https://hdl.handle.net/20.500.14352/124851 UL https://hdl.handle.net/20.500.14352/124851 LA eng NO Wang, X., Li, H., Wang, S., Martínez, M.-A., Ares, I., Martínez, M., Martínez-Larrañaga, M.-R., Wang, X., Anadón, A., & Maximiliano, J.-E. (2022). [Rev. of Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action]. Critical Reviews in Toxicology, 52(8), 664-680. https://doi.org/10.1080/10408444.2022.2143320 NO Ministerio de Ciencia e Innovación (España) DS Docta Complutense RD 18 mar 2026