RT Journal Article T1 Minimal Clinically Important Differences in Hand Pain Intensity (Numerical Pain Rate Scale) and Related-Function (Boston Carpal Tunnel Questionnaire) in Women With Carpal Tunnel Syndrome A1 López De Uralde Villanueva, Ibai Julio A1 Fernández de las Peñas, César A1 Cleland, Joshua A. A1 Cook, Chad A1 Llave Rincón, Ana I. de la A1 Valera Calero, Juan Antonio A1 Plaza Manzano, Gustavo AB ObjectiveTo calculate the minimal clinically important differences (MCIDs) for hand pain intensity and the Boston Carpal Tunnel Questionnaire (BCTQ) in a sample of women with carpal tunnel syndrome (CTS).DesignSecondary analysis of a randomized controlled trial.SettingA Hospital Rehabilitation Unit.ParticipantsOne hundred twenty women with clinical and electromyographic diagnosis of CTS who were randomly assigned into 2 groups (N=120).InterventionsOne group received 3 sessions of manual physical therapy (n=60) and the other group received surgery (n=60).Main Outcome MeasuresMean and the worst pain intensity (numerical pain rate scale, 0-10 points) and functional status and symptoms’ severity subscales of the BCTQ questionnaire were assessed before and 1 month after treatment. The Global Rating of Change (GROC) was used as the anchor variable for determining the MCID.ResultsA change of 1.5 and 2.5 points in mean and the worst pain intensity represents the MCID for Numerical Pain Rating Scale, whereas a change of 0.23 and 0.64 points in functional status and symptoms’ severity represents the MCID for each subscale of the BCTQ. All variables showed acceptable discrimination between patients classified as “improved” and those classified as “stable/not improved” (area under the curve≥0.72). Mean pain intensity (Youden index, 0.53; sensitivity: 73.3%; specificity: 80%) and symptoms’ severity (Youden index, 0.69; sensitivity: 90%; specificity: 77.8%) showed the best discriminative ability expressed as a percentage of prediction. Participants classified as “improved” had significantly greater improvements in pain intensity, functional status, and symptoms’ severity compared with those classified as “stable/not improved”.ConclusionA change of 1.5 and 2.5 points in mean and the worst pain and a change of 0.23 and 0.64 points in functional status and symptoms’ severity represents the MCID for pain intensity and BCTQ in women with CTS 1 month after treatment. PB Elsevier SN 0003-9993 YR 2024 FD 2024-01-30 LK https://hdl.handle.net/20.500.14352/104849 UL https://hdl.handle.net/20.500.14352/104849 LA eng NO López-de-Uralde-Villanueva, I., Fernández-de-Las-Peñas, C., Cleland, J. A., Cook, C., de-la-Llave-Rincón, A. I., Valera-Calero, J. A., & Plaza-Manzano, G. (2024). Minimal Clinically Important Differences in Hand Pain Intensity (Numerical Pain Rate Scale) and Related-Function (Boston Carpal Tunnel Questionnaire) in Women With Carpal Tunnel Syndrome. Archives of Physical Medicine and Rehabilitation, 105(1), 67-74. DS Docta Complutense RD 6 abr 2025