RT Journal Article
T1 Depletion of ARGs in antibiotic-resistance Klebsiella, Pseudomonas and Staphylococcus in hospital urines by electro and photo-electro disinfection
A1 Herraiz Carboné, Miguel
A1 Cotillas Soriano, Salvador
A1 Lacasa, Engracia
A1 Cañizares, Pablo
A1 Rodrigo, Manuel A.
A1 Sáez, Cristina
AB The depletion of blaKPC (K. pneumoniae), blaOXA-50 (P. aeruginosa) and mecA (S. aureus) genes from hospital urines is evaluated to contribute to solve the silent pandemic of antibiotic-resistance bacteria. A microfluidic flowthrough reactor with MMO anode and CB/PTFE cathode working at 50 A m− 2 is employed during electrodisinfection and photo-electrodisinfection processes. The electrodisinfection process only achieves an almost negligible removal of DNA and slightly log ARG increments of 0.18, 0.19 and 0.71 for blaOXA-50, mecA and blaKPC genes, respectively. Conversely, the photo-electrodisinfection process attains the complete disinfection for all ARB tested and logarithmic removals of 3.70, 2.25 and 0.82 for blaOXA-50, mecA and blaKPC genes, respectively. These outcomes emphasize the potential of the UV light coupled to the electrodisinfection process to promote the formation of not only hypochlorite but also chlorine and even nitrogen radicals, which contribute to enhance the disinfection efficiency of the target ARB and their ARGs.
PB Elsevier
SN 2214-7144
YR 2022
FD 2022-08-05
LK https://hdl.handle.net/20.500.14352/71904
UL https://hdl.handle.net/20.500.14352/71904
LA eng
NO CRUE-CSIC (Acuerdos Transformativos 2022)
NO Ministerio de Ciencia e Innovación (MICINN)
DS Docta Complutense
RD 10 abr 2025