%0 Journal Article
%A Garcillán Goyoaga, Beatriz de
%A Marín Marín, Ana Victoria
%A Jiménez Reinoso, Anaïs
%A Briones Contreras, Alejandro
%A Muñoz Ruiz, Miguel
%A García León, María J
%A Gil Calle, Juana Nelly
%A Allende Martínez, Luis Miguel
%A Martínez Naves, Eduardo
%A Toribio, Maria Luisa
%A Regueiro González-Barros, José Ramón
%T gd T lymphocytes in the diagnosis of human T cell receptorimmunodeficiencies
%D 2015
%@ 1664-3224
%U https://hdl.handle.net/20.500.14352/23905
%X Human T cell receptor (TCR) immunodeficiencies (TCRID) are rare autosomal recessive disorders caused by mutations affecting TCR, CD3, or CD247 chains, which share developmental, functional, and TCR expression defects (1).Their rapid diagnosis is fundamental for patient survival and early hematopoietic stemcell transplantation.Here,we propose that studying gd T cells, which are often neglected, can be helpful for a timely diagnosis. We thus offer a diagnostic flowchart and some lab tricks based on published cases.
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