RT Conference Proceedings
T1 Bactericidal activity of four disinfectant products against Legionella pneumophila serogroup 1
A1 García Esteban, María Teresa
A1 Pelaz, C.
AB lntroduction: Chlorine is a well known disinfectant in the treatment of cooling towers,frequently identified as origin of legionnaires' disease, and there is a few experiencein the use of other products.Objectives: This study describes the bactericida[ activity, in vitro, of tour disinfectantsused in cooling-towers against Legionella pneumophila serogroup 1 isolates.Methods: We tested the susceptibility of 28 clinical or environmental isolates of L.pneumophila serogroup 1 against tour disinfectants, chlorine and three disinfectantregistered in the Plaguicides Register: Adiclene 1352, Adicida 182 and PAB 17. Wedetermined the Minimal lnhibitory Concentration (MIC) by macrodilution method in BYEbroth , the Minimal Bactericidal Concentration (MBC) and the bactericidal effect.Results: The MIC50 and MIC90 values were similar (512 ppm far chlorine, 256 ppm farPAB 17, 8 ppm far Adicida 182 and 4 ppm far Adiclene 1352). The CMB values increasedno more than 3 twofold dilutions. All disinf ectants were a ble to produce at least a 104reduction in viable count of bacteria against all isolates to concentrations ?.2 ppm farchlorine, 8 ppm far PAB-17 and 16 ppm far Adiclene 1352 and Adicida 182. This reductionin all isolates was showed within 60min (rapidly bactericida[ effect) to concentrations?.4 ppm far chlorine, 128 ppm far PAB 17 and Adiclene 1352 and 256 ppm for Adicida182.Conclusions: All disinfectants showed rapid bactericidal activity to concentrationsrecommended by the man uf acturer in cooling-tower disinfections and slow bactericidaleffect to lower concentrations. Chlorine was the most effective with regard to bactericidaleffect. Chlorine and PAB-17 showed a decrease in activity when BYE broth medium wasused.
YR 2002
FD 2002-05
LK https://hdl.handle.net/20.500.14352/130360
UL https://hdl.handle.net/20.500.14352/130360
LA eng
DS Docta Complutense
RD 17 ene 2026