RT Journal Article T1 Genetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review A1 Gil Serna, Jessica A1 Vázquez Estévez, María Covadonga Inmaculada A1 Patiño Álvarez, Aurora Belén AB Mycotoxins are a significant food safety concern. Aflatoxins, trichothecenes, fumonisins, and ochratoxin A are considered the most important mycotoxins due to their frequent occurrence in food products and their well-known toxicity. The regulation of mycotoxin biosynthesis occurs mainly at transcriptional level, and specific regulators have been described in every biosynthetic cluster. Secondary metabolite production, including mycotoxin synthesis, is also regulated by general regulator pathways affected by light, osmotic stress and oxidative stress, among others. This review is focused on this genetic regulation of mycotoxin biosynthesis by specific genes and global regulators. PB Springer SN 1618-1905 YR 2019 FD 2019-05-29 LK https://hdl.handle.net/20.500.14352/12326 UL https://hdl.handle.net/20.500.14352/12326 LA eng NO Ministerio de Ciencia e Innovación (MICINN) DS Docta Complutense RD 27 abr 2025