RT Journal Article
T1 Sustained attention as a potential endophenotype for bipolar disorder
A1 Ancín, Inés
A1 Barabash Bustelo, Ana
A1 Teijeira, C
A1 Sánchez Morla, Eva María
A1 Bescós, Mará José
A1 Argudo, Isabel
A1 Torrijos, Sergio
A1 Vázquez‐Álvarez, Blanca
A1 López-Ibor Aliño, Juan José
A1 De La Vega Rodríguez, Irene
A1 Cabranes Díaz, José Antonio
AB Objective: Nowadays, it is accepted that to identify the biological basis of psychiatric illnesses it would be useful to deconstruct them into themost basic manifestations, such as cognitive deficits. The aim of this study was to set attention deficit as a stable vulnerability marker ofbipolar disorder.Method: Sustained attention was evaluated by the Continuous Performance Test (DS-CPT) in 143 euthymic bipolar patients and 105 controls. To estimate the influence of clinical profile in attention, patients completed a semi-structured interview.Results: Bipolar patients showed a deficit in attention during euthymic periods. This disturbance correlated with years of evolution, age of onset and age of first hospitalisation; and was not influenced by otherclinical data.Conclusion: Sustained attention may be considered as an endophenotype of the illness.
PB WILEY
SN 1600-0447
YR 2010
FD 2010
LK https://hdl.handle.net/20.500.14352/114892
UL https://hdl.handle.net/20.500.14352/114892
LA eng
NO Ancín, I., Santos, J. L., Teijeira, C., Sánchez‐Morla, E. M., Bescós, M. J., Argudo, I., Torrijos, S., Vázquez‐Álvarez, B., De La Vega, I., López‐Ibor, J. J., Barabash, A., & Cabranes‐Díaz, J. A. (2010). Sustained attention as a potential endophenotype for bipolar disorder. Acta Psychiatrica Scandinavica, 122(3), 235-245. https://doi.org/10.1111/j.1600-0447.2009.01532.x
NO Minsiterio de Ciencia, Innovación y Universidades, Fundación Mutua Madrileña, Agencia de Investigación e Innovación de Castilla-La Mancha
DS Docta Complutense
RD 8 abr 2025